Intracytoplasmic Spermatid Injection Can Result in the Delivery of Normal Offspring
نویسندگان
چکیده
منابع مشابه
Intracytoplasmic spermatid injection and in vitro maturation: fact or fiction?
Intracytoplasmic injection with testicular spermatozoa has become a routine treatment in fertility clinics. Spermatozoa can be recovered in half of patients with nonobstructive azoospermia. The use of immature germ cells for intracytoplasmic injection has been proposed for cases in which no spermatozoa can be retrieved. However, there are low pregnancy rates following intracytoplasmic injection...
متن کاملMultiple pregnancies obtained by testicular spermatid injection in combination with intracytoplasmic sperm injection.
Recent studies have shown that the injection of spermatid cells into the human oocyte can result in normal fertilization, embryo development and even delivery of live, healthy offspring. In our study, 23 azoospermic cases with severe spermatogenetic defects in their testicular biopsy are presented. The serum follicle stimulating hormone (FSH) concentrations and histopathological results of thes...
متن کاملRound spermatid injection.
This finding has caused great concern with round spermatid enthusiasts. A major complaint is that “one should not restrict the label of round spermatid only to those cells in which an acrosomal vesicle is visible” (p. 2977) (4). However, our observation is based not only on phase-contrast evaluation of TESE microdroplets but also on detailed stained histology of many hundreds of testis specimen...
متن کاملSuccessful pregnancy after spermatid injection.
We present nine cases of spermatid intracytoplasmic injection for the treatment of non-obstructive azoospermia. In eight cases, no elongated spermatids or spermatozoa were found in previous spermiograms or testicular biopsies. In these patients, treatment was performed using ejaculated (n = 6) and testicular (n = 2) retrieved round spermatids (Sa type). In cases where ejaculated round spermatid...
متن کاملMethods for isolation and purification of post-ejaculate human round spermatids for possible use in intracytoplasmic round spermatid injection*
Objective: To develop methods for the isolation and purification of round spermatids (RS) from ejaculated semen specimens recovered from patients suffering from nonobstructive azoospermia for the purpose of performing intracytoplasmic round spermatid injections (ROSI) into human oocytes. Design: Prospective study. Setting: Audrology Institute of Lexington, Lexington, Kentucky. Patients: Six men...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2003
ISSN: 0196-3635
DOI: 10.1002/j.1939-4640.2003.tb02738.x